Journal
ORGANIC LETTERS
Volume 8, Issue 10, Pages 2027-2030Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol060298j
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- NIGMS NIH HHS [GM33049, R01 GM033049, R01 GM033049-31] Funding Source: Medline
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The asymmetric synthesis of the oxindole alkaloid horsfiline is described. A palladium-catalyzed asymmetric allylic alkylation (AAA) is used to set the spiro(pyrrolidine-oxindole) stereogenic center.
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