Journal
LANCET
Volume 367, Issue 9522, Pages 1605-1617Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/S0140-6736(06)68699-6
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Cushing's syndrome results from lengthy and inappropriate exposure to excessive glucocorticoids. Untreated, it has significant morbidity and mortality. The syndrome remains a challenge to diagnose and manage. Here, we review the current understanding of pathogenesis, clinical features, diagnostic, and differential diagnostic approaches. We provide diagnostic algorithms and recommendations for management.
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