Journal
OPTICS LETTERS
Volume 31, Issue 10, Pages 1462-1464Publisher
OPTICAL SOC AMER
DOI: 10.1364/OL.31.001462
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- NCRR NIH HHS [RR019769] Funding Source: Medline
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We present a full-field phase microscopy technique for quantitative nanoscale surface profiling of samples in reflection. This technique utilizes swept-source optical coherence tomography in a full-field common path interferometer for phase-stable cross-sectional acquisition without scanning. Subwavelength variations in surface sample features are measured without interference from spurious reflections by processing the interferometric phase at a selected depth plane, providing a 1.3 nm stability for high signal-to-noise ratio surface features. Nanoscale imaging was demonstrated by measuring the location of receptor sites on a DNA assay biochip and the surface topography of erythrocytes in a blood smear. (c) 2006 Optical Society of America.
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