Journal
VACCINE
Volume 24, Issue 21, Pages 4490-4493Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.vaccine.2005.08.014
Keywords
electroporation; DNA vaccine; hepatitis B virus
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Funding
- NIAID NIH HHS [AI51833] Funding Source: Medline
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These studies document the ability of electroporation (EP)-based DNA vaccination to induce multi-specific CTL responses to hepatitis B virus (HBV) DNA vaccination in normal mice and marked immune responses to multivalent HBV DNA immunization in larger animal species. These results suggest that electroporation-mediated HBV DNA vaccination is worth pursuing as a treatment for chronic HBV infection. (c) 2005 Elsevier Ltd. All rights reserved.
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