Journal
INTERNATIONAL JOURNAL FOR PARASITOLOGY
Volume 36, Issue 6, Pages 651-659Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.ijpara.2006.02.010
Keywords
nematode; parasite; Caenorhabditis elegans; RNAi; gene function
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Funding
- Biotechnology and Biological Sciences Research Council [S20387] Funding Source: researchfish
- Biotechnology and Biological Sciences Research Council [S20387] Funding Source: Medline
- Wellcome Trust Funding Source: Medline
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Information on the functional genomics of Caenorhabditis elegans has increased significantly in the last few years with the development of RNA interference. In parasitic nematodes, RNA interference has shown some success in gene knockdown but optimisation of this technique will be required before it can be adopted as a reliable functional genomics tool. Comparative studies in C. elegans remain an appropriate alternative for studying the function and regulation of some parasite genes and will be extremely useful for fully exploiting the increasing parasite genome sequence data becoming available. (c) 2006 Australian Society for Parasitology Inc Published by Elsevier Ltd. All rights reserved.
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