Journal
FITOTERAPIA
Volume 77, Issue 4, Pages 321-323Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.fitote.2006.03.014
Keywords
Allium cepa; Allium sativum; ketoconazole; Malassezia furfur; Candida species; dermatophytes
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By using an agar dilution assay, the antifungal activity of aqueous extracts prepared from Allium cepa (onion; AOE) and Allium sativum (garlic; AGE) were evaluated against Malassezia furfur (25 strains), Candida albicans (18 strains), other Candida sp. (12 strains) as well as 35 strains of various dermatophyte species and compared with the activity of a known antifungal drug, ketoconazole (KTZ). All the AOE, AGE and KTZ were found to be able to inhibit growth of all fungi tested in a dose-dependent manner with maximum of 100% at defined concentrations. The results indicate that onion and garlic might be promising in treatment of fungal-associated diseases from important pathogenic genera Candida, Malassezia and the dermatophytes. (c) 2006 Elsevier B.V. All rights reserved.
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