4.3 Article

Synthesis and cytotoxicity studies of cyclohepta[b]indoles, benzo[6,7]cyclohepta[1,2-b]indoles, indeno[1,2-b]indoles, and benzo[a]carbazoles

Journal

JOURNAL OF THE CHINESE CHEMICAL SOCIETY
Volume 53, Issue 3, Pages 647-662

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/jccs.200600086

Keywords

indole; hydrazines; hydrazones; cytotoxicity; antineoplastic

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Synthesis and biological evaluation of various tricyclic and tetracyclic indoles are described. A number of these compounds possess in vitro activity against human nasopharyngeal carcinoma (HONE-1) and gastric adenocarcinoma (NUGC-3) cell lines.

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