Journal
AUSTRALIAN & NEW ZEALAND JOURNAL OF OBSTETRICS & GYNAECOLOGY
Volume 46, Issue 3, Pages 242-244Publisher
WILEY
DOI: 10.1111/j.1479-828X.2006.00585.x
Keywords
candidate gene; FOXL2; genetic disorder; inhibin; premature ovarian failure
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Premature ovarian failure (POF) is a common condition, affecting approximately 1:100 women. It is characterised by amenorrhea, hypoestrogenism, and elevated gonadotrophin levels in women under the age of 40. It is often an unexpected and distressing diagnosis, which coincides with infertility and menopausal symptoms. There is a well recognised genetic basis to the development of POF. Our laboratory has identified several candidate genes associated with POF.
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