Journal
AMERICAN JOURNAL OF OPHTHALMOLOGY
Volume 141, Issue 6, Pages 1131-1133Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/j.ajo.2006.01.049
Keywords
-
Categories
Funding
- NEI NIH HHS [EY-07544] Funding Source: Medline
Ask authors/readers for more resources
PURPOSE: To assess the diurnal and nocturnal persistency of intraocular pressure (IOP) reduction after omission of up to two doses of once-daily topical travoprost in patients with open,angle glaucoma or ocular hypertension. DESIGN: Prospective, open-label study. METHODS: Twenty subjects underwent three sessions of 24-hour IOP monitoring. The first session occurred before initiating treatment of newly diagnosed patients or after a four-week washout in patients already receiving medical therapy. The second session occurred after four weeks or more of travoprost treatment. The third session was performed 41 to 63 hours after the last travoprost dose. RESULTS: IOP lowering persisted after omission of one to two doses. Between 41 to 63 hours after the last dose, diurnal IOP reduction was attenuated, but nocturnal IOP reduction sustained. CONCLUSIONS: IOP lowering effect after omission of one to two doses of travoprost is attenuated in the diurnal period but sustained in the nocturnal period, the time corresponding to the highest baseline habitual IOP.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available