4.6 Article

BMP-2 gene polymorphisms and osteoporosis:: The Rotterdam Study

Journal

JOURNAL OF BONE AND MINERAL RESEARCH
Volume 21, Issue 6, Pages 845-854

Publisher

WILEY
DOI: 10.1359/JBMR.060306

Keywords

genetic; polymorphism; association; haplotypes; fractures

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After reported associations of variations in the BMP-2 gene with osteoporosis in small populations, we studied the association of the BMP-2 gene polymorphisms Ser37Ala and Arg190Ser with osteoporosis in 6353 men and women from the Rotterdam Study. We did not observe an association of these variants with BMD, bone loss, hip structural analysis parameters, and fracture risk.

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