Journal
ULTRASOUND IN MEDICINE AND BIOLOGY
Volume 32, Issue 6, Pages 857-874Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/j.ultrasmedbio.2006.02.1428
Keywords
elastography; elasticity; phantom; breast; ultrasound; MR
Funding
- NCI NIH HHS [R01 CA100373, R01CA100373, T32 CA009206] Funding Source: Medline
- NIBIB NIH HHS [R21 EB003853, R01 EB000459, R21EB003853, R01EB000459] Funding Source: Medline
Ask authors/readers for more resources
Two equivalent anthropomorphic breast phantoms were constructed, one for use in ultrasound elastography and the other in magnetic resonance (MR) elastography. A complete description of the manufacturing methods is provided. The materials used were oil-in-gelatin dispersions, where the volume percent oil differentiates the materials, primarily according to Young's moduli. Values of Young's moduli are in agreement with in vitro ranges for the corresponding normal and abnormal breast tissues. Ultrasound and nuclear magnetic resonance (NMR) properties are reasonably well represented. Phantoms of the type described promise to aid researchers who are developing hardware and software for elastography. Examples of ultrasound and MR elastograms of the phantoms are included to demonstrate the utility of the phantoms. Also, the level of stability of elastic properties of the component materials is quantified over a 15-month period. Such phantoms can serve as performance-assessing intermediaries between simple phantoms (consisting, for example, of homogeneous cylindrical inclusions in a homogeneous background) and a full-scale clinical trial. Thus, premature clinical trials may be avoided. (E-mail: elmadsen@wisc.edu) (c) 2006 World Federation for Ultrasound in Medicine & Biology.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available