4.5 Article

Explanation for the mechanical strength of amyloid fibrils

Journal

TRIBOLOGY LETTERS
Volume 22, Issue 3, Pages 233-237

Publisher

SPRINGER/PLENUM PUBLISHERS
DOI: 10.1007/s11249-006-9086-8

Keywords

biotribology; nanotribology; adhesion; AFM

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The presence of proteinaceous beta-sheet rich fibrillar structures and amyloidogenic material, has been alluded to extensively in the literature, in association with natural materials exhibiting superior mechanical strength per unit volume. Here we provide a clear experimental demonstration and explanation for why individual amyloid quaternary structures themselves have beneficial mechanical characteristics.

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