Journal
BIOLOGICAL CHEMISTRY
Volume 387, Issue 6, Pages 637-641Publisher
WALTER DE GRUYTER & CO
DOI: 10.1515/BC.2006.082
Keywords
cancer; evolution; hormone; inflammation; kininogen
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The human kallikrein locus on chromosome 19q13.3-13.4 contains kallikrein 1 - the tissue kallikrein - and 14 related serine proteases. Recent investigations into their function and evolution have indicated that the present nomenclature for these proteins is inadequate or insufficient. Here we present a new nomenclature in which proteins without proven kininogenase activity are denoted kallikrein-related peptidase. Names are also given to the unique rodent proteins that are closely related to kallikrein 1.
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