Journal
ADVANCED DRUG DELIVERY REVIEWS
Volume 58, Issue 3, Pages 377-386Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.addr.2006.01.022
Keywords
stent; stent design; drug eluting stent; restenosis
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More than 15 years have passed since stent technology was introduced by Sigwart et al. [U. Sigwart, J. Puel, V. Mirkovitch, F, Joffe, et al. Intravascular stents to prevent occlusion and restenosis after transluminal angioplasty. N. Engl. J. Med. 3 16 (1987) 701-706] among interventional cardiologists. Recently drug eluting stents have assumed dominance in the interventional world as positive trial results revealed their efficacy for preventing restenosis. Stent design, delivery-vehicle materials, and drug properties affect the function of these stents. Stainless steel stents with tubular and multicellular design have proven superior to coil or hybrid stent models. This chapter describes stents which have Subtle influences of modular design, metal coverage, strut thickness, strut shape, surface smoothness, and coating materials like ail alloy composition. (c) 2006 Elsevier B.V. All rights reserved.
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