Zinc oxide nanocomb biosensor for glucose detection

Single crystal zinc oxide nanocombs were synthesized in bulk quantity by vapor phase transport. A glucose biosensor was constructed using these nanocombs as supporting materials for glucose oxidase (GO,) loading. The zinc oxide nanocomb glucose biosensor showed a high sensitivity (15.33 mu A/cm(2) MM) for glucose detection and high affinity of GO(x) to glucose (the apparent K-M(app)=2.19 mM). The detection limit measured was 0.02 mM. These Michaelis-Menten constant K M results demonstrate that zinc oxide nanostructures have potential applications in biosensors. (c) 2006 American Institute of Physics.