Alginate-based nanofibrous scaffolds: Structural, mechanical, and biological properties

Alginate-based nanofibers with an average diameter of ca. 75 nm (see figure) have been fabricated by electrospinning. The nanofiber network has mechanical properties comparable to cartilage. The cellular compatibility is demonstrated with chondrocytes. This natural polymer-based nanofiber network may find application in tissue engineering and regenerative medicine.