Journal
ORGANIC LETTERS
Volume 8, Issue 12, Pages 2523-2526Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol060747f
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- NIGMS NIH HHS [R01 GM 073836-01] Funding Source: Medline
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This paper describes a mild palladium-catalyzed method for the regioselective chlorination, bromination, and iodination of arene C-H bonds using N-halosuccinimides as oxidants. These transformations have been applied to a wide array of substrates and can provide products that are complementary to those obtained via conventional electrophilic aromatic substitution reactions.
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