Journal
VASCULAR HEALTH AND RISK MANAGEMENT
Volume 2, Issue 2, Pages 157-162Publisher
DOVE MEDICAL PRESS LTD
DOI: 10.2147/vhrm.2006.2.2.157
Keywords
plant sterols; plant stanols; cardiovascular risk; cholesterol; LDL-cholesterol
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Plant sterol-enriched foods are an effective dietary adjuvant in reducing cardiovascular risk by lowering total cholesterol and low density lipoprotein-cholesterol (LDLC) in serum by up to similar to 15%. The mechanism of action of plant sterols is different from those of 3-hydroxy-3-methylglutaryl coenzyme A inhibitors (statins) and thus their effect is additive. Combining plant sterols with other dietary components known to reduce cholesterol in a portfolio approach has proven to be most effective for reduction of hypercholesterolemia and provide an alternative treatment option for clinicians. Plant sterol-enriched foods provides clinicians with a relatively cheap, safe, and effective way to help patients manage their cardiovascular risk.
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