Hydrothermal synthesis, crystal structure and antibacterial studies of nickel(II) and manganese(II) complexes with ciprofloxacin

Hydrothermal treatments of ciprofloxacin with Ni(NO3)(2) center dot 6H(2)O and Mn(ClO4)(2) center dot 6H(2)O yield two metal complexes: [Ni(H-cip)(2)(H2O)(2)](NO3)(2) center dot 2H(2)O (1) and [Mn(H-cip)(2)(H2O)(2)] (ClO4)(2) center dot 2H(2)O (2), confirmed by elemental analysis, IR and single crystal X-ray diffraction analyses. Complexes 1 and 2 were screened for antibacterial activity against Staphylococcus aureas, E. coli, Pseudomonas aeruginos and Candidaalbicans.