Journal
JOURNAL OF NATURAL PRODUCTS
Volume 69, Issue 6, Pages 871-875Publisher
AMER CHEMICAL SOC
DOI: 10.1021/np050201m
Keywords
-
Ask authors/readers for more resources
The three new 10-phenyl-[12]-cytochalasins Z(7), Z(8), and Z(9) (1-3), together with two known analogues, cytochalasins E ( 4) and K ( 5), were isolated from the marine-derived fungus Spicaria elegans. This is only the second report to date that cytochalasins contain a 12-membered macrocyclic ring. The structures of the three new cytochalasins were elucidated by spectroscopic methods, and their absolute configurations were determined for the first time by the modified Mosher's method. All five cytochalasins were evaluated for their cytotoxic effects on P388 and A-549 cell lines by the MTT method.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available