4.2 Review

(68)Gallium- and (90)Yttrium-/(177)Lutetium: theranostic twins for diagnosis and treatment of NETs

Journal

ANNALS OF NUCLEAR MEDICINE
Volume 29, Issue 1, Pages 1-7

Publisher

SPRINGER
DOI: 10.1007/s12149-014-0898-6

Keywords

Neuroendocrine tumor; Theranostic; SPECT/CT; PET/CT; PRRT; Radionuclide therapy

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Abundant expression of somatostatin receptors (SSTR) is frequently identified in differentiated neuroendocrine tumors and may serve as potential target for diagnostic imaging and treatment. This article discusses the theranostic approach of SSTR-targeting compounds including an overview of its role for diagnosis, staging and restaging, discussing its way to being established in clinical routine, and giving an outlook about further potentially relevant developments.

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