Journal
TETRAHEDRON
Volume 62, Issue 26, Pages 6405-6411Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2006.04.025
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Primary, secondary, and aromatic azides undergo 1,3 dipolar cycloaddition-coupling with an excess of alkyne in the presence of Cu(CH3CN)(4)PF6 as catalyst, N,N,N'-trimethylethylenediamine as ligand, molecular oxygen, and 4-methoxymorpholine N-oxide (NMO) as co-oxidant to afford 1,4,5-trisubstituted-1,2,3-triazoles. (c) 2006 Elsevier Ltd. All-rights reserved.
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