Journal
ADVANCED SYNTHESIS & CATALYSIS
Volume 348, Issue 10-11, Pages 1301-1305Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/adsc.200606060
Keywords
alkynes; aminopalladation-reductive elimination; cyclization; indoles; palladium
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2,3-Disubstituted indoles can be prepared in moderate to excellent yields by reacting readily available o-alkynyltrifluoroacetanilides with aryl chlorides in MeCN at 120 degrees C in the presence of Pd-2(dba)(3) and Xphos.
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