4.5 Article

Meningocele and ankyloblepharon following in utero exposure to olanzapine

Journal

EUROPEAN PSYCHIATRY
Volume 21, Issue 5, Pages 345-346

Publisher

ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER
DOI: 10.1016/j.eurpsy.2006.01.014

Keywords

olanzapine; ankyloblepharon; meningocele; teratogenicity

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Although atypical antipsychotics are widely used during pregnancy, their safety is not well established. This case highlights the possible teratogenic effect of olanzapine, in which the baby was born with meningocele and ankyloblepharon. It is suggested that olanzapine may interfere with embryonic development at different stages of pregnancy. (c) 2006 Elsevier SAS. All rights reserved.

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