Journal
ANNALS OF NEUROLOGY
Volume 73, Issue 1, Pages 10-15Publisher
WILEY
DOI: 10.1002/ana.23761
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Funding
- German Academic Exchange Service [A/07/95990]
- Alexander von Humboldt Foundation (Feodor-Lynen)
- Medical Research Fund of the University of Hamburg [NWF-04/07, NWF-11/09]
- German Research Foundation [SFB 936-C4]
- NIH
- Foundation for Medical Research
- Pfizer
- Boehringer Ingelheim
- Sanofi Aventis
- Bayer Vital
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Objective: Decline in cognitive functions, including impaired acquisition of novel skills, is a feature of older age that impacts activities of daily living, independence, and integration in modern societies. Methods: We tested whether the acquisition of a complex motor skill can be enhanced in old subjects by the application of transcranial direct current stimulation (tDCS) to the motor cortex. Results: The main finding was that old participants experienced substantial improvements when training was applied concurrent with tDCS, with effects lasting for at least 24 hours. Interpretation: These results suggest noninvasive brain stimulation as a promising and safe tool to potentially assist functional independence of aged individuals in daily life. ANN NEUROL 2013;73:10-15
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