Short duration large dose dexmedetomidine in a pediatric patient during procedural sedation

describe an infusion of dexmedetomidine at 1.0 mu g center dot kg(-1) center dot min(-1) for 10 min (total dose, 144 mu g) sedation in a 3-yr-old child weighing 14 kg. The large dose of dexmedetomidine produced a hemodynamically stable patient who was deeply sedated for approximately 4 h after discontinuing the infusion.