Journal
ADVANCED MATERIALS
Volume 18, Issue 13, Pages 1667-1671Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/adma.200600525
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Aptamer-linked smart materials responsive to a combination of any two analytes, including adenosine, cocaine, and K+, are demonstrated. The effect of small molecules on the properties of the nanomaterials can be either highly cooperative or non-cooperative, which can be described as logic gates with chemical inputs and colorimetric output (see figure).
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