Journal
TETRAHEDRON LETTERS
Volume 47, Issue 28, Pages 4807-4811Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2006.05.050
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Microwave activation coupled with Cu(I) catalysis, under solvent-free conditions, was found to dramatically enhance the 1,3-dipolar cycloaddition between azido-2'-deoxyribose and terminal alkynes. The process is highly efficient and quantitatively affords, in few minutes, the corresponding 4-substituted 1,2,3-triazolyl-nucleosides. (c) 2006 Elsevier Ltd. All rights reserved.
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