Journal
BIOCONJUGATE CHEMISTRY
Volume 17, Issue 4, Pages 873-876Publisher
AMER CHEMICAL SOC
DOI: 10.1021/bc060060f
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A stable cross-linked hydrogel was formed under mild aqueous conditions using pseudoproline peptide ligation chemistry. A cysteine-terminated lysine dendron containing four cysteines and a PEG macromolecule modified with terminal ester aldehydes were prepared. Upon mixing, the two macromers gave a stable hydrogel. This hydrogel along with sutures was used to successfully secure a corneal transplant in vitro.
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