An efficient method for the synthesis of acylals from aldehydes using silica-supported perchloric acid (HClO4-SiO2)

The synthesis of acylals from structurally diverse aldehydes has been performed in excellent yields under solvent-free conditions using HClO4-SiO2 as a mild, convenient, reusable. and heterogeneous catalyst. The procedure is operationally simple. environmentally benign and has the advantage of enhanced atom utilization. Furthermore. the catalyst can be recovered simply and reused efficiently a number of times without appreciable loss of activity. (c) 2006 Elsevier Ltd. All rights reserved.