Journal
TETRAHEDRON LETTERS
Volume 47, Issue 31, Pages 5507-5510Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2006.05.165
Keywords
fluorine and compounds; aldol reactions; amino acids and derivatives; asymmetric reactions
Categories
Ask authors/readers for more resources
L-Proline-catalyzed direct asymmetric aldol reaction of trifluoroacetaldehyde ethyl hemiacetal with unmodified ketones smoothly occurred at ambient temperature to produce beta-hydroxy-beta-trifluoromethylated ketones with good to excellent diastereo (up to 96% de) and enantioselectivities (up to 91% ee). (c) 2006 Elsevier Ltd. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
