Journal
AMERICAN JOURNAL OF CLINICAL PATHOLOGY
Volume 126, Issue 2, Pages 294-301Publisher
AMER SOC CLINICAL PATHOLOGY
DOI: 10.1309/6396QUBU6HEJBMPL
Keywords
urinary cytology; fluorescence in situ hybridization; continuing medical education; telecytology; e-learning
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Urinary cytology is limited by high interobserver variability in the evaluation of cells with little atypia. We set up an online quiz on urinary cytology and tested the performance of 246 international participants. The quiz consisted of still images of 42 urinary specimens with equivocal morphologic features and 10 control cases with an unequivocal cytologic diagnosis. The nature of the cells on the 292 quiz images had been verified by multitarget fluorescence in situ hybridization in addition to the information obtained by cystoscopy, clinical follow-up, and/or histologic examination. The original quiz cases and the percentage of answers given by the participants can be viewed at: http://kathrin.unibas.ch/urinzytol. High-grade cancers were diagnosed correctly in 76.0% and low-grade cancers in only 33.9%. Remarkably, 54.5% of all participants misclassifled decoy cells as malignant. This study shows that large-scale international online quizzes may be used to find educational deficits in cytopathology.
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