Journal
MOVEMENT DISORDERS
Volume 21, Issue 8, Pages 1277-1279Publisher
WILEY
DOI: 10.1002/mds.20896
Keywords
Parkinson's disease; end of dose dyskinesia; deep brain stimulation; DBS
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We report the therapeutic effects of deep brain stimulation (DBS) in 2 patients with Parkinson's disease (PD) with severe end of dose dyskinesia that was resistant to medical therapy. In both patients, severe, end of day ballistic dyskinesias occurred when the last levodopa dose of the day was wearing off. Globus pallidus (GPi) DBS in 1 case and subthalamic (STN) DBS in the second case produced full resolution of end of day dyskinesia. (C) 2006 Movement Disorder Society.
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