4.6 Article

Flap endonuclease 1 is overexpressed in prostate cancer and is associated with a high Gleason score

Journal

BJU INTERNATIONAL
Volume 98, Issue 2, Pages 445-451

Publisher

WILEY
DOI: 10.1111/j.1464-410X.2006.06224.x

Keywords

flap endonuclease 1; Gleason grade; prostate cancer; tissue microarray; tumour markers

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To investigate the expression and potential clinical usefulness of structure-specific flap endonuclease 1 (FEN-1) in human primary prostate cancer using tissue microarray technology, as FEN-1 was recently identified to be overexpressed in CL1.1, the most aggressive clone generated from the hormone-refractory prostate cancer cell line CL1.

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