Journal
ANNALS OF INDIAN ACADEMY OF NEUROLOGY
Volume 15, Issue 4, Pages 239-246Publisher
WOLTERS KLUWER MEDKNOW PUBLICATIONS
DOI: 10.4103/0972-2327.104323
Keywords
AD; atrophy; drug target; early Alzheimers; hippocampus; hippocampal atrophy; prevention
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Hippocampus is a complex brain structure embedded deep into temporal lobe. It has a major role in learning and memory. It is a plastic and vulnerable structure that gets damaged by a variety of stimuli. Studies have shown that it also gets affected in a variety of neurological and psychiatric disorders. In last decade or so, lot has been learnt about conditions that affect hippocampus and produce changes ranging from molecules to morphology. Progresses in radiological delineation, electrophysiology, and histochemical characterization have made it possible to study this archicerebral structure in greater detail. Present paper attempts to give an overview of hippocampus, both in health and diseases.
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