Journal
APPLIED AND ENVIRONMENTAL MICROBIOLOGY
Volume 72, Issue 8, Pages 5670-5672Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/AEM.00609-06
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Resveratrol production in Saccharomyces cerevisiae was compared to that in Escherichia coli. In both systems, 4-coumarate:coenzyme A ligase from tobacco and stilbene synthase from grapes were expressed. When p-coumaric acid was used as the precursor, resveratrol accumulations in the culture medium were observed to be comparable in E. coli (16 mg/liter) and yeast (6 mg/liter).
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