Journal
JOURNAL OF NEUROSURGERY
Volume 105, Issue 2, Pages 134-139Publisher
AMER ASSOC NEUROLOGICAL SURGEONS
DOI: 10.3171/ped.2006.105.2.134
Keywords
radiation therapy; intracranial aneurysm; vasculopathy; medulloblastoma; pediatric neurosurgery
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Ionizing radiation therapy is associated with pathological vascular changes in intracranial vessels, most commonly in the form of vessel thrombosis and occlusion. The development of an intracranial aneurysm following such therapy, however, is far less common. In this report the authors describe a 24-year-old man in whom a distal middle cerebral artery aneurysm developed 15 years after radiotherapy, which was given as adjuvant treatment following resection a medulloblastoma. The patient underwent a craniotomy for microsurgical trapping of the aneurysm and was discharged without any neurological deficit. This case serves to remind clinicians of the possibility, albeit rare, that intracranial aneurysms may form following cranial radiotherapy.
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