Journal
ACTA ODONTOLOGICA SCANDINAVICA
Volume 64, Issue 4, Pages 249-254Publisher
TAYLOR & FRANCIS AS
DOI: 10.1080/00016350600633243
Keywords
longitudinal studies; medications; xerostomia
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Funding
- NIDCR NIH HHS [R01 DE015260-01A1, R01 DE015260-03, R01 DE015260-02, R01 DE015260, R01 DE-015260-01A1] Funding Source: Medline
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Objective. To describe the prevalence and associations of xerostomia among adults in their early thirties, with particular attention to medication exposure as a putative risk factor. Material and Methods. The prevalence and associations of xerostomia were investigated among 32-year-old participants in a long-standing prospective cohort study. Some 950 individuals were assessed at ages 26 and 32 years, with medications being recorded on both occasions. Results. The prevalence of xerostomia was 10.0% ( with no apparent gender difference), and was significantly higher among those taking antidepressants ( odds ratio = 4.7), iron supplements ( OR = 4.1) or narcotic analgesics ( OR = 2.4). Those taking antidepressants at both ages 26 and 32 years had 22 times the odds of reporting xerostomia. Conclusion. Xerostomia may be a problem for a sizeable minority of young adults.
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