4.5 Review

P38 mitogen-activated protein kinase (MAPK) in rheumatoid arthritis

Journal

MINI-REVIEWS IN MEDICINAL CHEMISTRY
Volume 6, Issue 8, Pages 867-874

Publisher

BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/138955706777934982

Keywords

rheumatoid arthritis; drug; p38 MAPK

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The importance of p38 MAPK inhibitors as new drug for rheumatoid arthritis is reflected by the large number of compounds that has been developed over the last years. In this review new insights such as non-stressful activation of p38 MAPK, and the role of p38 MAPK in regulation of NF-kappa B recruitment are also discussed.

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