Journal
BIOMETRICAL JOURNAL
Volume 48, Issue 4, Pages 732-737Publisher
AKADEMIE VERLAG GMBH
DOI: 10.1002/bimj.200510233
Keywords
adaptive design; flexible design; group sequential; interim analysis; sample size calculation; software
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In this paper the currently available software we know for group sequential and adaptive designs is briefly reviewed. Stand-alone packages as well as modules within software packages or programming languages exist. New software developments for adaptive designs enable the user to perform data dependent design adaptations while controlling the Type I error rate.
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