Journal
CHEMICAL & PHARMACEUTICAL BULLETIN
Volume 54, Issue 8, Pages 1223-1225Publisher
PHARMACEUTICAL SOC JAPAN
DOI: 10.1248/cpb.54.1223
Keywords
Phyllanthus oligospermus; Euphorbiaceae; arylnaphthalene lignan; phyllanthusmin
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Three new arylnaphthalene lignans, namely phyllanthusmins A-C, together with nine known compounds were isolated and characterized from the stems and roots of Phyllanthus oligospermus by a bioassay-guided purification. The structures of the new compounds were elucidated by means of spectroscopic data interpretation. Among them, phyllanthusminA displayed significant cytotoxicity against KB and P-388 cancer cell lines.
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