Dirhodium tetracarboxylate derived from adamantylglycine as a chiral catalyst for carbenoid reactions

The dirhodium tetracarboxylate, Rh-2(S-PTAD)(4), derived from adamantylglycine, is a very effective chiral catalyst for carbenoid reactions. High asymmetric induction was obtained in Rh-2(S-PTAD)(4)-catalyzed intramolecular C-H insertion (94% ee), intermolecular cyclopropanation (99% ee), and intermolecular C-H insertion (92% ee).