Journal
JOURNAL OF ORGANIC CHEMISTRY
Volume 71, Issue 16, Pages 6277-6280Publisher
AMER CHEMICAL SOC
DOI: 10.1021/jo060839i
Keywords
-
Categories
Ask authors/readers for more resources
A short and efficient synthesis of (+)-spirolaxine methyl ether, a metabolite of the fungus Sporotrichum laxum with inhibitory activity against Helicobacter pylori, is described. The synthesis has been carried out by a Prins cyclization, to obtain the [ 6,5]-spiroketal system, and a Wadsworth-Emmons condensation, applied for the installation of the polymethylene chain on the phthalide moiety.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available