Journal
SCIENCE
Volume 313, Issue 5787, Pages 684-687Publisher
AMER ASSOC ADVANCEMENT SCIENCE
DOI: 10.1126/science.1128356
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- Wellcome Trust [078865] Funding Source: Medline
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Human choices are remarkably susceptible to the manner in which options are presented. This so-called framing effect represents a striking violation of standard economic accounts of human rationality, although its underlying neurobiology is not understood. We found that the framing effect was specifically associated with amygdala activity, suggesting a key role for an emotional system in mediating decision biases. Moreover, across individuals, orbital and medial prefrontal cortex activity predicted a reduced susceptibility to the framing effect. This finding highlights the importance of incorporating emotional processes within models of human choice and suggests how the brain may modulate the effect of these biasing influences to approximate rationality.
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