Journal
BIOINFORMATICS
Volume 22, Issue 16, Pages 2047-2048Publisher
OXFORD UNIV PRESS
DOI: 10.1093/bioinformatics/btl175
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Funding
- NCI NIH HHS [CA16042] Funding Source: Medline
- NIGMS NIH HHS [GM068955, GM008185] Funding Source: Medline
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BAli-Phy is a Bayesian posterior sampler that employs Markov chain Monte Carlo to explore the joint space of alignment and phylogeny given molecular sequence data. Simultaneous estimation eliminates bias toward inaccurate alignment guide-trees, employs more sophisticated substitution models during alignment and automatically utilizes information in shared insertion/deletions to help infer phylogenies.
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