Journal
OPTICS LETTERS
Volume 31, Issue 16, Pages 2453-2455Publisher
OPTICAL SOC AMER
DOI: 10.1364/OL.31.002453
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Funding
- NIBIB NIH HHS [R01 EB 000712, R01 EB000712] Funding Source: Medline
- NINDS NIH HHS [R01 NS046214, R01 NS 46214] Funding Source: Medline
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An in vivo photoacoustic imaging system was designed and implemented to image the entire small animal head. A special scanning gantry was designed to enable in vivo imaging in coronal cross sections with high contrast and good spatial resolution for the first time to our knowledge. By use of a 2.25 MHz ultrasonic transducer with a 6 mm diameter active element, an in-plane radial resolution of similar to 312 mu m was achieved. Deeply seated arterial and venous vessels in the head measuring up to 1.7 cm in diameter were simultaneously imaged in vivo with 804 nm wavelength laser excitation of photoacoustic waves. (c) 2006 Optical Society of America.
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