Journal
ACCOUNTS OF CHEMICAL RESEARCH
Volume 39, Issue 8, Pages 539-549Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ar068018n
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Funding
- NCI NIH HHS [CA103823] Funding Source: Medline
- NHLBI NIH HHS [HL25848] Funding Source: Medline
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The possibility for the application of organic synthesis to the discovery of new agents in combating neurodegenerative disorders is described. Our focus has been on agents derived from natural-product leads and natural products themselves prepared through total synthesis. Herein, we describe some of the chemistry as well as interesting observations made along the way.
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