Journal
ORGANIC LETTERS
Volume 8, Issue 17, Pages 3667-3670Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol061173h
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- NIGMS NIH HHS [R01 GM028961-26, R01 GM028961-25A1, GM-28961, R01 GM028961-24, R01 GM028961, R01 GM028961-23] Funding Source: Medline
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The synthesis of a C-1 - C-13 A-ring subunit of bryostatin 1 is detailed. The key features of the approach include the convergent fragment assembly with a highly stereoselective construction of the C-7-C-8 bond indicated above.
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