4.4 Article

Sequential regio and chemoselective cross-coupling reactions by means of O6-tri-isopropylsulfonate of 4-bromo-pyridazine 3,6-dione

Journal

TETRAHEDRON LETTERS
Volume 47, Issue 34, Pages 6125-6128

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2006.06.056

Keywords

4-bromo-pyridazine-3,6-dione; 3,6-dichloropyridazines; amination; palladium cross-coupling reaction; microwave heating; Suzuki reaction

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Regioselective desymmetrization of 4-substituted pyridazin-3,6-diones using sterically hindered 2,4,6-triisopropylphenyl-sulfonylchloride allowed efficient sequential palladium cross-coupling reactions. (c) 2006 Elsevier Ltd. All rights reserved.

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