4.4 Article

Latent fluorophores based on a Mannich cyclisation trigger

Journal

TETRAHEDRON LETTERS
Volume 47, Issue 35, Pages 6229-6233

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2006.06.138

Keywords

pro-fluorophore; fluorescent probe; penicillin G acylase

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We report the synthesis of a strongly blue-fluorescent pyrazino-benz[e]indole derivative, and its utility for enzyme sensing in biological assays through an original Mannich cyclisation triggered fluorescence unveiling. (c) 2006 Elsevier Ltd. All rights reserved.

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